Rifampicin Cas number:13292-46-1 Formulae hypotheticae C43H58N4O12

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Rifampicin Cas number:13292-46-1 Formulae hypotheticae C43H58N4O12

Description:

Cas numerus;13292-46-1

Nomen chemicumRifampicin

Formulae hypotheticae
C43H58N4O12

Synonyma:9,17,19,21-hexahydroxy-23-methoxy-2,4,12,1///;2,7-(epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b) furan-1,11(2-h)-dione,5,6;3-(((4-methyl-1-piperazinyl)imino)methyl)-rifamyci;3-((4-methyl-1-piperazinyl)iminomethyl )rifamycinsv;8-(((4-methyl-1-piperazinyl)imino)methyl)rifamycinsv;8-(4-Methylpiperazinyliminomethyl)rifamycinSV;8-(n-(4-methyl-1-piperazinyl)formidoyl)-rifomycins; RIFAMPIN "LEPETIT"


Product Detail

Product Tags

Products Specification

Liquescens punctum 183 °
Density 1.1782 (aspens estimate)
repono temp 2-8°C
solubility chloroform: soluble50mg/mL, clear
optical operatio N/A
Aspectus deliquium rubrum est valde tenebris rubrum
Puritas ≥99%

Descriptio

Rifampicin est semisynthetica derivatio rifamicin B, macrolactam antibioticam et plus quam quinque antibioticos ex mixtione rifamicins A, B, C, D, E, quae dicitur complexum rifamicin, quod producitur per actinomycetes Streptomyces mediteranei (. Nocardia mediteranei).In praxim medicam introducta anno 1968. Synthesis rifampicin incipit cum aquea solutione rifamicini, quae sub reactione condiciones oxidized in novam derivationem rifamicin S (32.7.4), cum media formatione rifamicin O (32.7. 3).Quinonem structuram huius facti reducendo cum hydrogenio utendo palladio in catalyst carbonis rifamicin SV (32.7.5).Productum inde aminomethylationem patitur mixtionem formaldehydi et pyrrolidini, dans 3-pyrrolidinomethylrifamicin SV (32.7.6).Productum oxidens inde cum tetracetate plumbi ad enamine et hydrolysim subsequentem cum solutione aquea ascorbici acidum 3-formylrifamicin SV (32.7.7).Regens hoc cum 1-amino-4-methylpiperazine rifampicin desideratum dat (32.7.8).

usus et dosis

Rifampin pro antibiotico adhibetur.Est derivatio semisynthetica rifamycin B, antibiotica macrocyclica a forma Streptomyces mediterranei producta.Rifampin adhibetur pro curatione tuberculosis, brucellosis, Staphlococcus aureus, et alii morbi infectiosi.

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